Te Whakamahinga o te Parahi Hydroxy Methionine 1

Ngā tono hua

1) ngā heihei parai

Ina ngā MMHAC (ngā chelate hydroxy methionine o te parahi, konutea, me te manganese) ki ngā kai heihei parai, i whakaatu ngā hua—ki te whakatauritea ki ngā kohuke iti kore-ora tuku iho—ko te whakaurunga o ngā MMHAC i tino whakanui ake i te taumaha o te tinana me te taumaha o te uaua o te huha, i pai ake ai te nakunaku o te parahi, ā, kāore he pānga kino ki te hauora o te puku me te wheua.

Ripanga 1. Taumaha tukatuka tinana (g/manu) me ngā kaute raina mā o te uma rakau me te uma o ngā heihei parai i whāngaihia ki te konutea, te parahi, me te manganese i te maimoatanga kai i te Rāhoroi 42.

Taonga	ITM	M10	T125	M30	SEM	Uara-P
Ū	684	716	719	713	14.86	0.415
Huha	397	413	412	425	7.29	0.078
Pahu	320	335	332	340	4.68	0.058
Huha me te rākau	717 a	748 ab	745 ab	765 b	11.32	0.050
Papa ngako	32.3	33.1	33.4	35.5	1.59	0.546
Ate	68.0	67.4	66.0	71.1	2.41	0.528
Ngākau	18.8	18.6	19.2	19.2	0.68	0.898
whatukuhu	9.49	10.2	10.6	10.6	0.51	0.413

Kia mōhio: ITM: Kohuke iti kore-waro 110 ppm Zn hei ZnSO4 16 ppm Cu hei CuSO4 me te 120 ppm Mn hei MnO e ai ki ngā taunakitanga kai a Ross 308;

M10: Ngā rahinga o te 40 ppm Zn 10 ppm Cu me te 40 ppm Mn hei chelate;

T125: Kohuke iti kore-waro 110 ppm Zn hei ZnSO4 me te 120 ppm Mn hei MnO e ai ki ngā aratohu Ross 308 me te 125 ppm Cu hei tribasic copper chloride (TBCC);

M30 = 40 ppm Zn, 30 ppm Cu, me te 40 ppm Mn hei chelate. He rerekē rawa ngā uara i te rarangi kotahi me ngā tuhinga whakarunga rerekē (P < 0.05).

2) Ngā poaka

I rangahauhia e tētahi rangahau ngā pānga o te whakakapinga wāhanga o ngā kohuke iti kore-waro ki ngā kohuke methionine hydroxy analogue chelates (MMHAC) i roto i ngā kai poaka kau mā ngā poaka kau me ā rātou pēpi. I whakaatuhia e ngā hua ko te tāpiringa MMHAC i whakaiti i te ngaronga taumaha tinana i roto i ngā poaka kau e whāngai ana, i whakatairanga i te pikinga taumaha tinana o te pēpi kau i te rā 18, i whakanui ake i ngā taumata histone acetylation uaua anga i te whānautanga, ā, i whakaiti i te whakaaturanga o ngā ira maha e pā ana ki te mumura me te whanaketanga uaua. I te nuinga, i whakapai ake te MMHAC i te hauora o te puku me te whanaketanga uaua i roto i ngā pēpi kau mā te whakahaere epigenetic me te whanaketanga, i whakarei ake i tō rātou pūmanawa tipu.

Ripanga 2 Ngā pānga tāpiri o te kohuke methionine hydroxy analogue chelate i roto i ngā kai poaka kau ki te whakaaturanga o te mRNA matua e pā ana ki te mumura o te jejunal i roto i te poaka ngote u

Taonga	ITM	CTM	SEM	P- uara
d 1 o te whāngai ū x 10^-5
IL-8	1344	1018	178	0.193
MUC2	5380	5511	984	0.925
NF-κB (p50)	701	693	93	0.944
NF-κB (p105)	1991	1646	211	0.274
TGF-b1	Mai i te tau 1991	1600	370	0.500
TNF-α	11	7	2	0.174
d 18 o te whāngai ū x 10^-5
IL-8	1134	787	220	0.262
MUC2	5773	3871	722	0.077

Tuhipoka: Interleukin-8 (IL-8), mucin-2 (MUC2), nuclear factor-κB (NF-κB), transforming growth factor-1 (TGF-1), me te tumor necrosis factor-α (TNF-α)

ITM = ngā pūtake kore-waro tuku iho o ngā kohuke iti (0.2% te taumata whakaurunga ki roto i ngā kai)

CTM = 50:50 kohuke methionine hydroxy analogue chelate me ngā kohuke kore-waro (0.2% taumata whakaurunga ki roto i ngā kai)

3)Ngā manu ruminant

I roto i ngā kau miraka e whāngai ana i te pēpi, me whakakapi te haurua o te konupora whanariki kite parahi hauwai metioninai tino whakapiki ake i te kukū parahi i roto i te toto, i whakapai ake i te ngāwari o te nakunaku o te muka hopi horoi kūpapa (NDF) me te muka hopi horoi waikawa (ADF), ā, i whakarei ake i te hua miraka me te 4% o te hanga miraka kua whakatikatikaina te ngako. E whakaatu ana ēnei kitenga he rautaki kai whai hua ake te whakakapi wāhanga i te konupora whanariki ki te (HMTBA)₂-Cu i roto i ngā kai kau miraka.

Ripanga 3 Ngā pānga o te methionine hydroxy Cu [(HMTBA)2-Cu] ki te hanganga miraka o ngā kau

Taonga	S	SM	M	SEM	Uara-P
DMI, kg/rā	19.2	20.3	19.8	0.35	0.23
Te hua o te miraka, kg/rā	28.8	33.8	31.3	1.06	0.08
Ngako, %	3.81	3.74	3.75	0.06	0.81
Pūmua, %	3.34	3.28	3.28	0.04	0.19
Te rakatose, %	4.48	4.35	4.43	0.05	0.08
SNF, %	8.63	8.84	8.63	0.05	0.33
Te hua ngako, kg/rā	1.04	1.22	1.10	0.04	0.09
Te hua o te pūmua, kg/rā	0.92	0.92	0.90	0.03	0.72
Te hua o te lactose, kg/rā	1.23	1.23	1.21	0.04	0.45
Urea N, mg/dL	18.39	17.70	18.83	0.45	0.19
4% FCM, kg/rā	26.1	30.1	27.5	0.91	0.06

Ngā Maimoatanga: S = Cu sulfate anake: 12 mg o Cu e whakaratohia ana e te CuSO4 mō ia kirokaramu o te kukū; SM = Cu sulfate me te (HMTBA)2-Cu: 6 mg o Cu e whakaratohia ana e te CuSO4, me tētahi atu 6 mg o Cu e whakaratohia ana e te (HMTBA)2-Cu mō ia kirokaramu o te kukū; M = (HMTBA)2-Cu anake: 12 mg o Cu e whakaratohia ana e te (HMTBA)2-Cu mō ia kirokaramu o te kukū.